IgE-mediated acute asthma following inhalation of a powdered marine sponge

Clin Allergy. 1982 Mar;12(2):179-86. doi: 10.1111/j.1365-2222.1982.tb01637.x.


IgE-antibodies reactive with extracts of a number of different marine invertebrate-species were demonstrated in the serum of a laboratory worker who experienced an acute attack of asthma following occupational exposure to powdered marine-organisms. Histamine was liberated from the patient's blood following in vitro challenge with sponge extract. The desirability of knowing the atopic status of employees in certain occupations is stressed.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Allergens
  • Animals
  • Asthma / etiology
  • Asthma / immunology*
  • Histamine Release
  • Humans
  • Immunoglobulin E / biosynthesis*
  • Male
  • Occupational Diseases / etiology
  • Occupational Diseases / immunology*
  • Porifera / immunology*
  • Powders
  • Radioallergosorbent Test
  • Receptors, Mitogen
  • Skin Tests


  • Allergens
  • Powders
  • Receptors, Mitogen
  • Immunoglobulin E