Fluoride-resistant acid phosphatase-containing neurones in dorsal root ganglia are separate from those containing substance P or somatostatin

Neuroscience. 1982 Jan;7(1):89-97. doi: 10.1016/0306-4522(82)90155-5.

Abstract

The distribution of fluoride-resistant acid phosphatase, substance P and somatostatin were investigated in the dorsal horn of the spinal cord and in dorsal root ganglia. In the dorsal horn, the distribution of fluoride-resistant acid phosphatase closely paralleled that of somatostatin and only partly overlapped with that of substance P. In sensory ganglia, none of the fluoride-resistant acid phosphatase-containing neurones contained either substance P or somatostatin. The results suggest the existence of a population of fluoride-resistant phosphatase-positive sensory neurones which is distinct from neurones containing either of these peptides.

Publication types

  • Comparative Study

MeSH terms

  • Acid Phosphatase / metabolism*
  • Animals
  • Drug Resistance
  • Fluorides / pharmacology
  • Ganglia, Spinal / cytology
  • Ganglia, Spinal / metabolism*
  • Male
  • Neurons, Afferent / metabolism
  • Rats
  • Rats, Inbred Strains
  • Somatostatin / metabolism*
  • Spinal Cord / metabolism*
  • Substance P / metabolism*

Substances

  • Substance P
  • Somatostatin
  • Acid Phosphatase
  • Fluorides