Filtering valve implant for neovascular glaucoma in proliferative diabetic retinopathy

Ophthalmology. 1982 Mar;89(3):286-9. doi: 10.1016/s0161-6420(82)34810-1.


The prevention and treatment of neovascular glaucoma in diabetic patients presents a difficult clinical challenge. This report presents the pathologic findings in a juvenile onset diabetic patient who underwent panretinal photocoagulation. She subsequently developed neovascular glaucoma, was treated with the the Krupin-Denver valve implant, and received cyclocryotherapy after the filtering surgery failed to maintain a normal intraocular pressure. The pathologic findings resulting from each treatment modality are presented with emphasis on the failed intraocular valve. A fibrous ingrowth surrounded the valve, and a foreign body granulomatous response was present.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Cryosurgery / methods
  • Diabetic Retinopathy / complications*
  • Diabetic Retinopathy / physiopathology
  • Equipment Failure
  • Eye / pathology*
  • Female
  • Filtration
  • Glaucoma / etiology
  • Glaucoma / surgery*
  • Humans
  • Intraocular Pressure / drug effects
  • Laser Therapy
  • Lasers / adverse effects
  • Neovascularization, Pathologic
  • Timolol / therapeutic use


  • Timolol