Pregnancy in mixed connective tissue disease: comparison with systemic lupus erythematosus

J Rheumatol. Jul-Aug 1982;9(4):549-55.

Abstract

The risk of pregnancy was evaluated in 31 patients with mixed connective tissue disease (MCTD), 31 patients with systemic lupus erythematosus (SLE) and 51 controls. The fertility rates in MCTD and SLE were unaltered by disease; however, parity was decreased and fetal wastage was increased both before and even more so after onset. It is our observation that pregnancy carries the same risks in MCTD as it does in SLE.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Antibodies, Antinuclear / analysis
  • DNA / immunology
  • Epitopes / immunology
  • Female
  • Fetal Death / etiology
  • Humans
  • Lupus Erythematosus, Systemic / diagnosis*
  • Lupus Erythematosus, Systemic / immunology
  • Mixed Connective Tissue Disease / diagnosis*
  • Mixed Connective Tissue Disease / immunology
  • Neutrophils
  • Pregnancy
  • Pregnancy Complications / diagnosis*
  • Pregnancy Complications / immunology
  • Prognosis
  • Ribonucleoproteins / immunology
  • Risk

Substances

  • Antibodies, Antinuclear
  • Epitopes
  • Ribonucleoproteins
  • DNA