Kinetics of deamination of 5-aza-2'-deoxycytidine and cytosine arabinoside by human liver cytidine deaminase and its inhibition by 3-deazauridine, thymidine or uracil arabinoside

Biochem Pharmacol. 1983 Apr 1;32(7):1327-8. doi: 10.1016/0006-2952(83)90293-9.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3-Deazauridine / pharmacology
  • Adult
  • Arabinofuranosyluracil / pharmacology
  • Azacitidine / analogs & derivatives*
  • Azacitidine / metabolism
  • Cytarabine / metabolism
  • Cytidine Deaminase / antagonists & inhibitors
  • Cytidine Deaminase / metabolism*
  • Cytosine / metabolism*
  • Decitabine
  • Humans
  • Kinetics
  • Liver / enzymology*
  • Nucleoside Deaminases / metabolism*
  • Substrate Specificity
  • Thymidine / pharmacology

Substances

  • Cytarabine
  • 3-Deazauridine
  • Arabinofuranosyluracil
  • Decitabine
  • Cytosine
  • Nucleoside Deaminases
  • Cytidine Deaminase
  • Azacitidine
  • Thymidine