Transitory macrophages in the white matter of the developing visual cortex. I. Light and electron microscopic characteristics and distribution

Brain Res. 1983 Dec;313(1):39-53. doi: 10.1016/0165-3806(83)90200-6.

Abstract

Injections of horseradish peroxidase (HRP) into the occipital cortex of the kitten and diffusing to the white matter label a widely distributed microglial population and in addition, cells with light and electron microscopic features of 'gitter cells'. The latter are concentrated in a complex and highly consistent system of interconnected clusters in the white matter of the lateral, postlateral, middle suprasylvian and posterior ectosylvian gyri, as well as on the roof of the lateral ventricle. The 'gitter cells' have the ultrastructural and (as described by others) chemical characteristics of macrophages, and may be involved in the elimination of transitory axons.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging
  • Animals
  • Animals, Newborn
  • Axonal Transport
  • Cats
  • Horseradish Peroxidase
  • Macrophages / cytology
  • Macrophages / physiology*
  • Microscopy, Electron
  • Visual Cortex / cytology
  • Visual Cortex / growth & development*
  • Visual Cortex / ultrastructure

Substances

  • Horseradish Peroxidase