Corticotropin-releasing factor is contained within perikarya and nerve fibres of rat duodenum

Biochem Biophys Res Commun. 1984 Jul 18;122(1):381-7. doi: 10.1016/0006-291x(84)90486-8.


Immunofluorescence microscopic studies revealed a corticotropin-releasing factor (CRF) staining within both myenteric plexus perikarya and nerve fibres of the rat duodenum. A CRF-immunofluorescence could be visualized also within nerve fibres close associated with myenteric and submucous blood vessels. Even the lamina propria contained CRF-immunoreactive nerve fibres, which were obviously often localized near the basal lamina.

MeSH terms

  • Animals
  • Corticotropin-Releasing Hormone / isolation & purification*
  • Duodenum / innervation*
  • Fluorescent Antibody Technique
  • Histocytochemistry
  • Intestinal Mucosa / analysis
  • Male
  • Myenteric Plexus / analysis*
  • Nerve Fibers / analysis*
  • Neurons / analysis*
  • Rats
  • Rats, Inbred Strains
  • Staining and Labeling


  • Corticotropin-Releasing Hormone