Acute organophosphate poisoning presenting with choreo-athetosis

J Toxicol Clin Toxicol. 1984;22(2):187-91. doi: 10.3109/15563658408992554.


Although it is known that extrapyramidal function is dependent upon a balance between cholinergic and dopaminergic effects, only anti-dopaminergic substances commonly induce extrapyramidal symptoms. This paper describes a patient who ingested chlorpyrifos and presented with choreo-athetosis and depressed cholinesterases. She responded to atropine therapy and made a complete recovery. Although not often described excessive cholinergic activity may also produce extrapyramidal symptoms.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Atropine / therapeutic use
  • Chlorpyrifos / poisoning*
  • Cholinesterases / blood
  • Dyskinesia, Drug-Induced / drug therapy
  • Dyskinesia, Drug-Induced / physiopathology*
  • Extrapyramidal Tracts / drug effects
  • Female
  • Humans


  • Atropine
  • Cholinesterases
  • Chlorpyrifos