PIP: The Horizon program has examined the real problems and dilemmas which occurred with the introduction of the drug Depo-Provera. This contraceptive drug is given by injection, and the men of the villages in the nether regions of Burma and Thailand are taught to inject their spouses. This will then prevent pregnancy for at least 6 months. All seems to be going well thus far. The method is relatively inexpensive, convenient, and involves all members of the community rather than having costly medical aids to administer the drug. Additionally, Depo-Provera is effective and reliable. Yet, the program has raised some disturbing issues. One of these is that the safety factor appears to have been ignored. Questions have been raised about the size effects of this drug, and it was banned in the U.S. in 1978 because the authorities were seriously concerned about the possible carcinogenic effects of the drug. In Britain, Depo-Provera is only permitted in exceptional cases and under strictly controlled conditions. In Thailand, Horizon discovered that physicians have to balance the obvious problems of poverty and overcrowding that would result from not using the drug.