This report is devoted to the populational description of the Ashkhabad district. Examination of one of the typical agricultural villages (Izgant of the Ashkhabad district) gave the main parameters of the population. The total number of the inhabitants studied is 1596, the proportion of the studied is 56%, the average family size for the parent with completed reproduction period being 5.47, the average generation time - 33 to 38, the gametic index - 0.67 and the inbreeding coefficient - 0.002267. The distribution of some markers (ABO, MN, Hp, Rh, Pp) have been studied. A rather low coefficient of inbreeding, as a result of the absence of geographical isolation, may account for incidence of autosomal recessive disorders.