Abstract
A mouse hybrid cell line secreted monoclonal antibody which reacted specifically with Streptococcus mutans 6715 (serotype g) glucosyltransferase (GTase)-synthesizing water-insoluble glucan and inhibited with enzyme reaction. The antibody was cross-reactive with GTase of serotype d but not with GTase of other serotypes of S. mutans when an enzyme-linked immunosorbent assay was used.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibodies, Monoclonal / analysis
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Antibodies, Monoclonal / biosynthesis*
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Cross Reactions
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Glucosyltransferases / immunology*
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Hybridomas / immunology
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Mice
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Mice, Inbred BALB C
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Serotyping
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Streptococcus mutans / enzymology
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Streptococcus mutans / immunology*
Substances
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Antibodies, Monoclonal
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Glucosyltransferases