Production of monoclonal antibody against a glucosyltransferase of Streptococcus mutans 6715

Infect Immun. 1983 Aug;41(2):872-5. doi: 10.1128/iai.41.2.872-875.1983.

Abstract

A mouse hybrid cell line secreted monoclonal antibody which reacted specifically with Streptococcus mutans 6715 (serotype g) glucosyltransferase (GTase)-synthesizing water-insoluble glucan and inhibited with enzyme reaction. The antibody was cross-reactive with GTase of serotype d but not with GTase of other serotypes of S. mutans when an enzyme-linked immunosorbent assay was used.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Monoclonal / analysis
  • Antibodies, Monoclonal / biosynthesis*
  • Cross Reactions
  • Glucosyltransferases / immunology*
  • Hybridomas / immunology
  • Mice
  • Mice, Inbred BALB C
  • Serotyping
  • Streptococcus mutans / enzymology
  • Streptococcus mutans / immunology*

Substances

  • Antibodies, Monoclonal
  • Glucosyltransferases