Gastrointestinal endoscopy and HBV infection: no evidence for a causal relationship. A prospective controlled study

Gastrointest Endosc. 1984 Feb;30(1):15-7. doi: 10.1016/s0016-5107(84)72286-3.


The importance of the different endoscopic procedures in the transmission of hepatitis B was investigated prospectively by following up for 6 months all HBV-negative patients endoscoped from April to October 1981. A group of patients admitted in the same period to our unit constituted the control group. Controls were obtained after 1, 3, and 6 months from endoscopy. Infection rate was 1% for the control group and 0.45% for the endoscopy group. The difference is not statistically significant. These results strongly support the view, already present on an uncontrolled basis in the literature, that transmission of hepatitis B is not associated with gastrointestinal endoscopy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cholangiopancreatography, Endoscopic Retrograde / adverse effects
  • Colonoscopy / adverse effects
  • Endoscopy / adverse effects*
  • Gastroscopy / adverse effects
  • Hepatitis B / immunology
  • Hepatitis B / transmission*
  • Hepatitis B Core Antigens / analysis
  • Hepatitis B Surface Antigens / analysis
  • Humans
  • Laparoscopy / adverse effects
  • Prospective Studies


  • Hepatitis B Core Antigens
  • Hepatitis B Surface Antigens