Abstract
The activities of ciprofloxacin and norfloxacin against 100 mycobacteria isolates were studied in vitro by the 1% standard proportion method. Ciprofloxacin was more active against M. tuberculosis and M. fortuitum with MICs of 1.0 and 0.25 microgram/ml, respectively, against 90% of isolates; norfloxacin had MICs of 8.0 and 2.0 micrograms/ml, respectively, against 90% of isolates.
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Antitubercular Agents / pharmacology*
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Ciprofloxacin
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Drug Interactions
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Microbial Sensitivity Tests
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Mycobacterium avium / drug effects
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Mycobacterium tuberculosis / drug effects
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Nalidixic Acid / analogs & derivatives*
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Nalidixic Acid / pharmacology
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Norfloxacin
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Quinolines / pharmacology*
Substances
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Anti-Bacterial Agents
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Antitubercular Agents
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Quinolines
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Nalidixic Acid
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Ciprofloxacin
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Norfloxacin