Allergic contact dermatitis to compound tincture of benzoin

J Am Acad Dermatol. 1984 Nov;11(5 Pt 1):847-50. doi: 10.1016/s0190-9622(84)80462-4.


Nineteen cases of allergic contact dermatitis to compound tincture of benzoin are described. Patch testing to individual components revealed positive reactions to all ingredients except aloe. An alternative preparation, Mastisol, was successfully used without primarily inducing allergy. It should be considered for use before benzoin because once allergy to benzoin exists, cross-reactions to Mastisol usually occur. This is probably due to the presence of a common ingredient, styrax gum.

Publication types

  • Case Reports
  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Blister / drug therapy*
  • Child
  • Drug Eruptions / etiology*
  • Female
  • Foot Dermatoses / chemically induced
  • Humans
  • Male
  • Mastic Resin
  • Military Medicine
  • Patch Tests
  • Physical Exertion
  • Plant Extracts / adverse effects
  • Plant Extracts / therapeutic use
  • Resins, Plant / adverse effects
  • Resins, Plant / therapeutic use
  • Styrax


  • Benzoin Gum
  • Mastic Resin
  • Plant Extracts
  • Resins, Plant