Development of fiber types in human fetal muscle. An immunocytochemical study

J Neurol Sci. 1984 Oct;66(1):107-15. doi: 10.1016/0022-510x(84)90146-1.


Human fetal muscles have been studied using immunocytochemical methods with antibodies directed against different myosin isoforms. We show that fiber type differences can be detected as early as 15-16 weeks of gestation. At this time it would appear that both the heavy and light chains characteristic of slow myosin are found in some myotubes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphatases / metabolism
  • Humans
  • Immunoenzyme Techniques
  • Muscles / cytology
  • Muscles / embryology*
  • Muscles / metabolism
  • Myosins / metabolism*


  • Adenosine Triphosphatases
  • Myosins