Assignment of the human gene for phosphoglycolate phosphatase to chromosome 16

R S Sparkes; T Mohandas; M C Sparkes; M B Passage; J D Shulkin

doi:10.1007/BF00278965

Assignment of the human gene for phosphoglycolate phosphatase to chromosome 16

Hum Genet. 1980;54(2):159-61. doi: 10.1007/BF00278965.

Authors

R S Sparkes, T Mohandas, M C Sparkes, M B Passage, J D Shulkin

PMID: 6248449
DOI: 10.1007/BF00278965

Abstract

Seventeen independently derived primary mouse-human hybrid clones were scored for the expression of human phosphoglycolate phosphatase (PGP) by electrophoresis and for the presence of human chromosomes with the aid of Q banding. The correlation of biochemical and cytogenetic analyses shows that the segregation of human PGP in these hybrids is concordant only with human chromosome 16, thus enabling the assignment of the genetic locus for PGP to human chromosome 16.

Publication types

Research Support, U.S. Gov't, P.H.S.

MeSH terms

Animals
Chromosome Mapping
Chromosomes, Human, 16-18 / ultrastructure*
Humans
Hybrid Cells
In Vitro Techniques
Mice
Phenotype
Phosphoric Monoester Hydrolases / genetics*

Substances

phosphoglycolate phosphatase
Phosphoric Monoester Hydrolases