The tophus in calcium pyrophosphate deposition disease

JAMA. 1980 Oct 10;244(15):1711-2.


A 61-year-old man had a tophus on the third finger of his right hand. There was no history of arthritis, no laboratory abnormality, and no chondrocalcinosis. Crystalline material from the tophus was identified as calcium pyrophosphate dihydrate by x-ray diffraction.

Publication types

  • Case Reports

MeSH terms

  • Calcium Pyrophosphate / analysis
  • Calcium Pyrophosphate / metabolism*
  • Chondrocalcinosis / diagnosis*
  • Diphosphates / metabolism*
  • Fingers
  • Humans
  • Male
  • Metabolic Diseases / diagnosis
  • Middle Aged
  • X-Ray Diffraction


  • Diphosphates
  • Calcium Pyrophosphate