Novel cell cycle control of RNA synthesis in yeast

Nature. 1978 Feb 23;271(5647):726-30. doi: 10.1038/271726a0.

Abstract

During the fission yeast cell cycle, the rate of polyadenylated messenger RNA synthesis doubles when the cell reaches a critical size. This size-related control maintains average mRNA content in balance with total cell mass during exponential growth, even in cells growing at different absolute growth rates per cell.

MeSH terms

  • Ascomycota / metabolism*
  • Cell Cycle*
  • DNA Replication
  • Mutation
  • Poly A / biosynthesis
  • RNA, Messenger / biosynthesis*
  • Schizosaccharomyces / cytology
  • Schizosaccharomyces / growth & development
  • Schizosaccharomyces / metabolism*

Substances

  • RNA, Messenger
  • Poly A