Isolation of a recombinant influenza virus (Hsw 1 N2) from swine in Japan

Arch Virol. 1980;66(3):271-4. doi: 10.1007/BF01314741.


Outbreaks of swine influenza were first observed in Japan in 1978. A number of influenza viruses were isolated from diseased swine. Almost all viruses isolated were swine influenza virus (Hsw 1 N1) but two viruses isolated from the nasal swabs of swine showing clinical signs of influenza in the Kanagawa prefecture were characterized antigenically as Hsw 1 N2. Analysis of swine sera showed that influenza virus Hsw 1 N2 was epidemic in the farm from which the virus had been isolated. The new virus (Hsw 1 N2) seems to have been produced by recombination between swine influenza virus (Hsw 1 N1) and Hong Kong influenza virus (H3N2).

MeSH terms

  • Animals
  • Antibodies, Viral / analysis
  • Influenza A virus / genetics*
  • Influenza A virus / immunology
  • Influenza A virus / isolation & purification
  • Orthomyxoviridae Infections / microbiology*
  • Recombination, Genetic*
  • Swine
  • Swine Diseases / microbiology*


  • Antibodies, Viral