Antihypertensive activity of N-[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-Ala-L-Pro (MK-421), an orally active converting enzyme inhibitor

MeSH terms

• Administration, Oral
• Angiotensin I / antagonists & inhibitors
• Angiotensin-Converting Enzyme Inhibitors*
• Animals
• Antihypertensive Agents / pharmacology*
• Antihypertensive Agents / therapeutic use
• Blood Pressure / drug effects
• Dipeptides / pharmacology*
• Disease Models, Animal
• Dogs
• Drug Therapy, Combination
• Enalapril
• Female
• Hydrochlorothiazide / therapeutic use
• Hypertension / drug therapy
• Hypertension, Renal / drug therapy
• Male
• Nephrectomy
• Rats
• Renin / blood