Linitis plastica caused by metastatic lobular carcinoma of the breast

Mayo Clin Proc. 1980 Dec;55(12):747-53.


We describe herein the syndrome of linitis plastica caused by metastatic lobular carcinoma of the breast. In 14 of our 31 patients, gastric involvement, alone or concurrent with other metastasis, provided the first sign of tumor dissemination. The distinction of primary and secondary gastric malignancies in patients with a history of breast cancer is most important for successful management of patients. At a time when primary gastric carcinoma is decreasing nationally, an awareness of the association of lobular breast tumors with linitis plastica due to metastases may modify diagnostic evaluation and treatment planning in patients who present with symptoms of this syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Scirrhous / secondary*
  • Adult
  • Aged
  • Breast Neoplasms / pathology*
  • Carcinoma / pathology*
  • Female
  • Humans
  • Linitis Plastica / diagnosis
  • Linitis Plastica / pathology
  • Linitis Plastica / secondary*
  • Middle Aged
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / pathology
  • Stomach Neoplasms / secondary*