Gynecomastia with ketoconazole

Antimicrob Agents Chemother. 1981 Jun;19(6):1073-4. doi: 10.1128/AAC.19.6.1073.

Abstract

Three of forty men developed bilateral gynecomastia upon ketoconazole treatment. Symptoms abated despite continued therapy. This appears to be a direct drug effect on breast tissue.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Aged
  • Antifungal Agents / adverse effects*
  • Gynecomastia / chemically induced*
  • Humans
  • Imidazoles / adverse effects*
  • Ketoconazole
  • Male
  • Middle Aged
  • Piperazines / adverse effects*

Substances

  • Antifungal Agents
  • Imidazoles
  • Piperazines
  • Ketoconazole