[Neurobrucellosis: report of 3 cases]

Arq Neuropsiquiatr. 1981 Jun;39(2):203-13. doi: 10.1590/s0004-282x1981000200009.
[Article in Portuguese]


Three cases of probable neurobrucellosis are reported. The diagnosis was made on the basis of immunological tests. Two patients with a clinical picture of meningomyelitis showed a definitive clinical improvement under tetracycline and streptomycin therapy. The immunological reactions found in the record case were even more positive in the spinal fluid than in the blood. In the case 3 with a clinical presentation of cerebral hemorrhage the histopathological studies demonstrated non specific chronic leptomeningitis and local hemorrhages in the caudate nucleus bilaterally. The diagnose and treatment of neurobrucellosis are discussed, stressing the importance of an early therapy.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Brucella / isolation & purification
  • Brucellosis / diagnosis*
  • Brucellosis / drug therapy
  • Cerebral Hemorrhage / diagnosis
  • Female
  • Humans
  • Male
  • Meningitis / diagnosis
  • Meningitis / etiology*
  • Myelitis / diagnosis
  • Myelitis / etiology*
  • Peripheral Nervous System Diseases / etiology*
  • Serologic Tests
  • Tetracycline / therapeutic use


  • Tetracycline