Calcium pyrophosphate dihydrate deposition disease and familial hypomagnesemia

J Rheumatol. Sep-Oct 1981;8(5):767-71.

Abstract

A 40-year-old woman presented with calcium pyrophosphate synovitis and chondrocalcinosis. She was subsequently found to have hypomagnesemia, as did her 22-year-old son. Metabolic studies demonstrated normal gastrointestinal absorption of magnesium, and impaired renal conservation of magnesium without other evidence of renal tubular dysfunction. It seems likely that a genetically determined abnormality of magnesium metabolism was responsible for the occurrence of chondrocalcinosis in this patient.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Calcium / metabolism
  • Calcium Pyrophosphate / physiology*
  • Chondrocalcinosis / complications
  • Crystallization
  • Digestive System / metabolism
  • Diphosphates / physiology*
  • Female
  • Humans
  • Magnesium / metabolism
  • Magnesium Deficiency / complications
  • Magnesium Deficiency / genetics*
  • Magnesium Deficiency / metabolism
  • Synovitis / complications

Substances

  • Diphosphates
  • Magnesium
  • Calcium
  • Calcium Pyrophosphate