Polyoma Virus Capsid Structure at 22.5 A Resolution

Nature. 1982 Jan 14;295(5845):110-5. doi: 10.1038/295110a0.

Abstract

X-ray diffraction data from polyoma capsid crystals were phased by refinement of low-resolution starting models to obtain a self-consistent structural solution. The unexpected result that the hexavalent morphological unit is a pentamer shows that specificity of bonding is not conserved among the protein subunits in the icosahedrally symmetric capsid.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Capsid*
  • Fourier Analysis
  • Macromolecular Substances
  • Models, Molecular
  • Polyomavirus / ultrastructure*
  • Protein Conformation
  • Viral Proteins*
  • X-Ray Diffraction

Substances

  • Macromolecular Substances
  • Viral Proteins