An outbreak of infectious hepatitis investigated using radioimmunoassays for hepatitis A virus antibody

J Hyg (Lond). 1982 Apr;88(2):351-4. doi: 10.1017/s0022172400070194.

Abstract

An outbreak of suspected infectious hepatitis in a primary school was investigated using sensitive diagnostic methods for hepatitis A. A total of 116 sera from children were tested for the presence of both IgM and IgG antibodies to hepatitis A (HAV). The results were compared to those obtained for samples from a control school. IgG antibodies were present in 45% and 10% of the children in the outbreak and control schools respectively.

MeSH terms

  • Antibodies, Viral / analysis*
  • Child
  • Child, Preschool
  • Disease Outbreaks*
  • England
  • Hepatitis A / epidemiology*
  • Hepatovirus / immunology
  • Humans
  • Immunoglobulin G / analysis
  • Immunoglobulin M / analysis
  • Male
  • Radioimmunoassay
  • Schools

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Immunoglobulin M