A common sequence in the inverted terminal repetitions of human and avian adenoviruses

Gene. 1982 May;18(2):193-7. doi: 10.1016/0378-1119(82)90117-2.

Abstract

The termini of the avian chick embryo lethal orphan (CELO) virus DNA have been sequenced. The results revealed a 63-bp-long inverted terminal repetition (ITR) which shared the sequence ATAATA with all adenovirus termini, thus far analyzed. The CELO virus ITR differed from those of the mammalian adenoviruses in two major aspects: (i) it is not a perfect duplication; (ii) it begins with a 5'-guanylic acid residue instead of the cytidylic acid normally observed in adenoviruses.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoviridae / genetics*
  • Adenoviruses, Human / genetics*
  • Animals
  • Aviadenovirus / genetics*
  • Base Composition
  • DNA Restriction Enzymes
  • DNA, Viral / genetics*
  • Humans
  • Plasmids
  • Repetitive Sequences, Nucleic Acid
  • Species Specificity

Substances

  • DNA, Viral
  • DNA Restriction Enzymes