Epstein-Barr virus in nasopharyngeal and salivary gland carcinomas of Greenland Eskimoes

Br J Cancer. 1982 Nov;46(5):721-8. doi: 10.1038/bjc.1982.264.

Abstract

Biopsy specimens from nasopharyngeal carcinomas (NPC) or salivary-gland carcinomas (SGC) in Greenland Eskimoes were examined for the presence of Epstein-Barr virus (EBV) DNA and sera from the patients were tested for EBV-specific antibody titres. Six out of 7 NPCs and one from an undifferentiated SGG were positive for EBV DNA. The EBV-specific antibody spectra and titres of the patients with NPC or undifferentiated SGG conformed to the results of earlier studies in other high-incidence areas.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Antibodies, Viral / analysis
  • DNA, Viral / analysis
  • Female
  • Greenland
  • Herpesvirus 4, Human* / immunology
  • Humans
  • Inuits*
  • Male
  • Middle Aged
  • Nasopharyngeal Neoplasms / analysis
  • Nasopharyngeal Neoplasms / immunology
  • Nasopharyngeal Neoplasms / microbiology*
  • Salivary Gland Neoplasms / analysis
  • Salivary Gland Neoplasms / immunology
  • Salivary Gland Neoplasms / microbiology*

Substances

  • Antibodies, Viral
  • DNA, Viral