Prolactin receptors in human breast cancer

Eur J Cancer Clin Oncol. 1982 Nov;18(11):1157-62. doi: 10.1016/0277-5379(82)90097-9.


Prolactin receptors have been measured in 92 human breast carcinomas. Both free and total receptors (after desaturation by MgCl2) have been looked for. Free receptors have been found in 46% of the cases, total receptors in 72%. Specific binding ranges from 0.8 to 8.0%. No correlation could be found between prolactin receptors and age, weight, menopausal status and pathological features (differentiation, histoprognostic grading, cellular density). A highly significant correlation has been found between prolactin receptors on the one hand and estradiol and progesterone receptors on the other.

MeSH terms

  • Adenocarcinoma / immunology*
  • Body Weight
  • Breast Neoplasms / immunology*
  • Female
  • Humans
  • Menopause
  • Prognosis
  • Receptors, Cell Surface / analysis*
  • Receptors, Estradiol
  • Receptors, Estrogen / analysis
  • Receptors, Progesterone / analysis
  • Receptors, Prolactin


  • Receptors, Cell Surface
  • Receptors, Estradiol
  • Receptors, Estrogen
  • Receptors, Progesterone
  • Receptors, Prolactin