On the presence of two new high mobility group-like proteins in HeLa S3 cells

FEBS Lett. 1983 Feb 21;152(2):163-7. doi: 10.1016/0014-5793(83)80370-6.

Abstract

Two phosphorylated HMG-like proteins with Mr approximately 10 000 have been isolated from HeLa S3 cells, one being present in metaphase and one in interphase cells. The amino acid compositions of these proteins are very similar but differ from the known HMG proteins. However, they exhibit similarities being rich in proline, basic and acidic amino acids. A possible role in chromatin condensation of the HMG-like protein characteristic for metaphase cells is suggested.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chemical Phenomena
  • Chemistry, Physical
  • Chromosomal Proteins, Non-Histone / metabolism*
  • Electrophoresis, Polyacrylamide Gel
  • HeLa Cells
  • High Mobility Group Proteins
  • Humans
  • Hydrolysis
  • Interphase
  • Metaphase
  • Phosphoric Monoester Hydrolases
  • Phosphorus Radioisotopes

Substances

  • Chromosomal Proteins, Non-Histone
  • High Mobility Group Proteins
  • Phosphorus Radioisotopes
  • Phosphoric Monoester Hydrolases