Packed column chromatography, high-resolution gas-chromatography and high pressure liquid chromatography in comparison for the analysis of cannabis constituents

Forensic Sci Int. 1983 Mar-Apr;21(2):129-37. doi: 10.1016/0379-0738(83)90101-9.


The identification and the quantitative estimation of cannabis constituents is important for forensic purposes. High resolution gas-chromatography gives better results than gas-liquid chromatography with packed columns, as it shows a better resolution and higher number of constituents. Different quantitative values were found with the two chromatographic procedures. High-pressure liquid chromatography revealed the presence of cannabinoid acids in fresh cut influorescences of cannabis plants. The ratio acid/neutral cannabinoid may be useful in supplying information about the age of the cannabis preparations.

Publication types

  • Comparative Study

MeSH terms

  • Cannabidiol / analysis
  • Cannabinoids / analysis*
  • Cannabinol / analysis
  • Cannabis / analysis*
  • Chromatography / methods*
  • Chromatography, Gas / methods
  • Chromatography, High Pressure Liquid / methods
  • Dronabinol / analysis


  • Cannabinoids
  • Cannabidiol
  • Dronabinol
  • Cannabinol
  • cannabichromene