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. 1983 Nov 17-23;306(5940):234-8.
doi: 10.1038/306234a0.

A Polymorphic DNA Marker Genetically Linked to Huntington's Disease

A Polymorphic DNA Marker Genetically Linked to Huntington's Disease

J F Gusella et al. Nature. .

Abstract

Family studies show that the Huntington's disease gene is linked to a polymorphic DNA marker that maps to human chromosome 4. The chromosomal localization of the Huntington's disease gene is the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder.

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