An efficient program to construct restriction maps from experimental data with realistic error levels

Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):703-16. doi: 10.1093/nar/12.1part2.703.

Abstract

A novel algorithm has been developed to map restriction fragments, starting from experimental size values with realistic error rates. A high performing PASCAL program has been derived from this algorithm to construct linear maps in minimal computation times.

MeSH terms

  • Base Sequence
  • Computers*
  • DNA / genetics*
  • DNA Restriction Enzymes*
  • Microcomputers*
  • Nucleic Acid Hybridization
  • Software*
  • Statistics as Topic

Substances

  • DNA
  • DNA Restriction Enzymes