Soft tissue responses to hydroxylapatite particles of different shapes

J Oral Maxillofac Surg. 1984 Mar;42(3):150-60. doi: 10.1016/s0278-2391(84)80025-7.


Fifteen beagle dogs seven to 15 months of age had 0.5 g of hydroxylapatite in the form of sharp-edged particles (HA-1) or rounded particles (HA-2) implanted in buccal soft tissue pouches. Tissue specimens from each site were obtained at two weeks, six weeks, three months, and six months. A mild inflammatory response was seen at the implant sites with both particle shapes; however, inflammation resolved at a faster rate in the sites implanted with round hydroxylapatite particles.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Dental Implantation*
  • Dogs
  • Durapatite
  • Foreign-Body Reaction / pathology
  • Granulation Tissue / anatomy & histology
  • Hydroxyapatites*
  • Mouth Mucosa / anatomy & histology*
  • Stomatitis / pathology
  • Surface Properties


  • Hydroxyapatites
  • Durapatite