A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes

Nature. 1984 Mar 29-Apr 4;308(5958):428-33. doi: 10.1038/308428a0.


A repetitive DNA sequence has been identified in the Drosophila melanogaster genome that appears to be localized specifically within genes of the bithorax and Antennapedia complexes that are required for correct segmental development. Initially identified in cloned copies of the genes Antennapedia, Ultrabithorax and fushi tarazu, the sequence is also contained within two other DNA clones that have characteristics strongly suggesting that they derive from other homoeotic genes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Cloning, Molecular*
  • DNA / isolation & purification*
  • DNA Restriction Enzymes
  • Drosophila melanogaster / anatomy & histology
  • Drosophila melanogaster / genetics*
  • Nucleic Acid Hybridization
  • Repetitive Sequences, Nucleic Acid
  • Transcription, Genetic


  • DNA
  • DNA Restriction Enzymes