[Influence of administration of pyridoxine on circadian rhythm of plasma ACTH, cortisol prolactin and somatotropin in normal subjects]

Boll Soc Ital Biol Sper. 1984 Feb 28;60(2):273-8.
[Article in Italian]

Abstract

The influence of vitamin B6 in a dosage of 300 mg X 2 in 24 hrs, on circadian rhythm of plasmatic ACTH, cortisol, prolactin and somatotropin have been studied in 10 normal women. After vitamin B6 24 hrs pattern of ACTH and cortisol is unchanged; prolactin levels are slightly lower, in a statistically unsignificant proportion the night peak of growth hormone is higher in a statistically significant proportion (p. 0.05). The effect of vitamin B6 is likely to me mediated by dopaminergic receptors at hypothalamic level as previous studies by other Authors appear to prove.

Publication types

  • English Abstract

MeSH terms

  • Adrenocorticotropic Hormone / blood*
  • Adult
  • Circadian Rhythm / drug effects
  • Female
  • Growth Hormone / blood*
  • Humans
  • Hydrocortisone / blood*
  • Middle Aged
  • Prolactin / blood*
  • Pyridoxine / pharmacology*
  • Reference Values

Substances

  • Adrenocorticotropic Hormone
  • Prolactin
  • Growth Hormone
  • Pyridoxine
  • Hydrocortisone