The authors report the case of a 28-year-old man with a solitary adenoma of the liver. The tumor was detected because of a raised erythrocyte sedimentation rate and serum fibrinogen. Review of the literature shows that adenoma of the liver is an uncommon tumor in man since only 30 other cases have been reported. The tumor is often multiple (55 p. 100) and the clinical manifestations are quite different from those observed in women: the adenoma is often asymptomatic (45 p. 100) and rupture is rare (10 p. 100). Androgens seem to be implicated in the development of adenoma in man since 8 out of 31 patients had received androgens for a long period of time; androgens also seem to favor the tumor's rupture.