Hepatocellular carcinoma in patients with acute intermittent porphyria

Acta Med Scand. 1984;215(3):271-4. doi: 10.1111/j.0954-6820.1984.tb05005.x.


In a retrospective study over a 20-year period we found in the Umeå region in Sweden 11 patients (7 women and 4 men, mean age 67 years) with both hepatocellular carcinoma and acute intermittent porphyria. This coincidence was highly significant. Concomitant existence of portal cirrhosis of the liver was demonstrated in those 5 patients in whom it could be examined.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Carcinoma, Hepatocellular / complications*
  • Female
  • Humans
  • Liver Neoplasms / complications*
  • Male
  • Middle Aged
  • Porphyrias / complications*
  • Retrospective Studies
  • Sex Factors
  • Sweden