Invasive pulmonary aspergillosis associated with aspergilloma in sarcoidosis

Abstract

We have described two patients with corticosteroid-treated sarcoidosis and with autopsy-proven aspergilloma and diffuse invasive pulmonary aspergillosis. In one, growth of the fungus within a cyst was probably followed by progression to diffuse pulmonary infection. In the second, lung necrosis from invasive infection may have led to the formation of the mycetoma found at autopsy.