Immunological significance of Aspergillus fumigatus in cane-sugar mills

Arch Environ Health. 1983 Jan-Feb;38(1):41-6. doi: 10.1080/00039896.1983.10543977.

Abstract

An aeromycological study has revealed the preponderance of Aspergillus fumigatus at the bagasse-containing sites in sugar-cane mills located in the northwestern part of the Punjab State. The fungus was frequently isolated from the sputum cultures of the mill workers and a significant number of the workers were positive reactors when challenged intracutaneously with aspergillin. Immediate Type I and late Arthus Type skin hypersensitivity was observed in 10.6% and 4.4%, respectively, of the 548 workers investigated. Incidence of hypersensitivity was particularly high among workers having chronic respiratory problems. During a sample survey of 238 workers having chronic respiratory diseases, diagnoses of allergic bronchopulmonary aspergillosis, and allergic bronchopulmonary candidiasis based on positive clinical and laboratory findings, were made in 17 (7.1%) and in only 4 (1.7%) of the cases, respectively. Evidence is presented to support that the epidemiology of allergic bronchopulmonary aspergillosis, but not of allergic bronchopulmonary candidiasis, may have an occupational dimension.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aspergillosis, Allergic Bronchopulmonary / diagnosis
  • Aspergillosis, Allergic Bronchopulmonary / immunology*
  • Aspergillus fumigatus / immunology
  • Aspergillus fumigatus / isolation & purification
  • Candidiasis / diagnosis
  • Candidiasis / immunology
  • Humans
  • Occupational Diseases / diagnosis
  • Occupational Diseases / immunology*
  • Respiratory Hypersensitivity / diagnosis
  • Respiratory Hypersensitivity / immunology
  • Skin Tests
  • Sputum / microbiology