The conservative treatment of fissure-in-ano

Br J Surg. 1983 Mar;70(3):175-6. doi: 10.1002/bjs.1800700312.


A randomized clinical trial assessed the value of regular anal dilatation in combination with a topical local anaesthetic in the treatment of 82 patients with a posterior fissure-in-ano. One month after treatment the fissure had healed in 43.6 per cent of patients using 2 per cent lignocaine gel alone and in 41.9 per cent of patients who also used a St Mark's Hospital anal dilator. Thus the regular use of such a dilator did not contribute to the success of conservative therapy in patients with a posterior anal fissure. A review of patients who presented with anterior or lateral anal fissures during the trial period revealed that healing was achieved in 73.3 per cent of patients without operation within 1 month of diagnosis.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Administration, Topical
  • Adolescent
  • Adult
  • Aged
  • Clinical Trials as Topic
  • Dilatation*
  • Female
  • Fissure in Ano / therapy*
  • Humans
  • Lidocaine / therapeutic use*
  • Male
  • Middle Aged
  • Random Allocation


  • Lidocaine