Evaluation in young children of the Urabe Am 9 strain of live attenuated mumps vaccine in comparison with the Jeryl Lynn strain

Acta Paediatr Scand. 1983 Jan;72(1):37-40. doi: 10.1111/j.1651-2227.1983.tb09660.x.

Abstract

Urabe Am 9, a new strain of mumps vaccine, originally developed in Japan, was evaluated in children 14 to 20 months of age in a comparative trial with the Jeryl Lynn strain. Both vaccines performed well. The antibody responses were measured using a neutralization test and a haemolysis-in-gel test. The seroconversion rates at six weeks, as detected with either one or both tests, were 55/58 (94.8%) after the Urabe Am 9 and 58/60 (96.7%) after the Jeryl Lynn vaccine. Only mild infrequent adverse reactions were observed. It is concluded that both strains of live attenuated mumps vaccine are immunogenic and well-tolerated in this age group.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Viral / analysis
  • Clinical Trials as Topic
  • Humans
  • Infant
  • Mumps Vaccine / adverse effects
  • Mumps Vaccine / immunology*
  • Vaccines, Attenuated / adverse effects
  • Vaccines, Attenuated / immunology*

Substances

  • Antibodies, Viral
  • Mumps Vaccine
  • Vaccines, Attenuated