Results obtained with piracetam in foetal distress during labour

J Int Med Res. 1983;11(3):129-36. doi: 10.1177/030006058301100301.


A double-blind study was performed on ninety-six parturients of the Lima Maternity Hospital, Peru, with some evidence of foetal distress who were given indistinguishably piracetam or a placebo at random in order to investigate the effects of the drug on the foetus. The conditions of the new-born babies who had received piracetam were superior to those of the babies treated with the placebo, as evaluated with the Apgar at 1, 5 and 10 minutes after birth and on the basis of the neurological and clinical examination as from 24 hours until they were released. In addition, the reduction of the duration of the labour in the patients treated with piracetam as compared with the control group was obvious.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Amniotic Fluid / analysis
  • Apgar Score
  • Birth Weight
  • Clinical Trials as Topic
  • Female
  • Fetal Blood / analysis
  • Fetal Distress / drug therapy*
  • Fetal Heart / physiology
  • Heart Rate
  • Humans
  • Hydrogen-Ion Concentration
  • Infant, Newborn
  • Obstetric Labor Complications / drug therapy*
  • Piracetam / administration & dosage
  • Piracetam / therapeutic use*
  • Placenta / anatomy & histology
  • Pregnancy
  • Pyrrolidinones / therapeutic use*
  • Random Allocation
  • Time Factors


  • Pyrrolidinones
  • Piracetam