Immunological characterization of an ocular adnexal lymphoid T tumor by monoclonal antibodies

Ophthalmologica. 1983;187(1):43-9. doi: 10.1159/000309300.


The phenotype of a lymphoid orbital tumor is described, using monoclonal antibodies of the OKT series. The majority of tumor cells lacked surface immunoglobulins and bound OKT3, hence they arose from the T lineage. These cells belonged to the mature helper T cell subpopulation since a great proportion was recognized by OKT4 antibody. In contrast, a decrease in the peripheral blood OKT4+ pool was observed. The results demonstrate the importance of using a panel of markers, such as monoclonal antibodies, for the identification of cell derivation of lymphomas.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antibodies, Monoclonal / immunology*
  • Female
  • Fluorescent Antibody Technique
  • Humans
  • Lymphoma / immunology*
  • Orbital Neoplasms / immunology*
  • Phenotype
  • Receptors, Antigen, B-Cell / analysis
  • T-Lymphocytes / immunology*


  • Antibodies, Monoclonal
  • Receptors, Antigen, B-Cell