Intrastromal noninflammatory bacterial colonization of a corneal graft

Arch Ophthalmol. 1983 Nov;101(11):1749-52. doi: 10.1001/archopht.1983.01040020751018.


Progressive branching, needlelike stromal opacities were observed within a corneal transplant. Analysis of the corneal button by light microscopy and transmission electron microscopy disclosed a localized epithelial ingrowth into the stroma at a suture tract accompanied by intrastromal pockets of gram-positive cocci extending across the cornea. No inflammatory reaction was found in the areas of bacterial colonization. To our knowledge, noninflammatory bacterial colonization of the stroma of a corneal transplant has not been previously described.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Bacterial Infections*
  • Cornea / microbiology*
  • Corneal Opacity / etiology*
  • Corneal Transplantation*
  • Female
  • Gram-Positive Bacteria / isolation & purification
  • Humans
  • Microscopy, Electron
  • Sutures