Effects of hyperbaric oxygen and hyperbaric air on the survival of island skin flaps

Plast Reconstr Surg. 1984 Jan;73(1):27-30. doi: 10.1097/00006534-198401000-00005.


The effects of hyperbaric air and oxygen on skin survival were studied in acute 8 X 8 cm neurovascular island flaps in rats. Skin flaps treated with hyperbaric 8% oxygen (equivalent to room air at standard pressure) exhibited no improvement in skin survival. Skin flaps treated with hyperbaric air (21% oxygen) and hyperbaric 100% oxygen exhibited significant increases in survival.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Air Pressure
  • Air*
  • Animals
  • Evaluation Studies as Topic
  • Female
  • Graft Survival*
  • Hyperbaric Oxygenation*
  • Rats
  • Rats, Inbred Strains
  • Skin Transplantation*
  • Surgical Flaps*