Pharmacologic trials in the treatment of cerebellar tremor

Arch Neurol. 1984 Mar;41(3):280-1. doi: 10.1001/archneur.1984.04050150058017.


We studied the effect of long-term administration of propranolol hydrochloride and isoniazid and the acute action of ethyl alcohol on cerebellar tremor in patients with multiple sclerosis and primary cerebellar degeneration in a placebo-controlled double-blind crossover test. None of the drugs decreased the severity of either static or kinetic cerebellar tremors.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Cerebellar Diseases / drug therapy*
  • Clinical Trials as Topic
  • Double-Blind Method
  • Ethanol / administration & dosage*
  • Humans
  • Isoniazid / administration & dosage*
  • Male
  • Middle Aged
  • Multiple Sclerosis / drug therapy
  • Propranolol / administration & dosage*
  • Tremor / drug therapy*


  • Ethanol
  • Propranolol
  • Isoniazid