Enchondromatosis (Ollier's disease) and ovarian juvenile granulosa cell tumor

Cancer. 1984 Apr 1;53(7):1605-8. doi: 10.1002/1097-0142(19840401)53:7<1605::aid-cncr2820530731>3.0.co;2-n.


An ovarian juvenile granulosa cell tumor in a 15-year-old white girl is reported. The patient had enchondromatosis (Ollier's disease). amd a review of the literature revealed two previous reports linking enchondromatosis with ovarian sex-cord stromal tumors. This heretofore unrecognized association between these two unusual lesions indirectly supports a generalized mesodermal dysplasia in patients with enchondromatosis. It also draws attention to the possible emergence of ovarian neoplasms in addition to the more frequently encountered chondrosarcomas.

Publication types

  • Case Reports
  • Comparative Study
  • Review

MeSH terms

  • Adolescent
  • Female
  • Granulosa Cell Tumor / complications*
  • Granulosa Cell Tumor / pathology
  • Humans
  • Laparotomy
  • Osteochondrodysplasias / complications*
  • Ovarian Neoplasms / complications*
  • Ovarian Neoplasms / pathology