The long-term results of the use of human amnion in the treatment of leg ulcers

Br J Plast Surg. 1984 Apr;37(2):191-3. doi: 10.1016/0007-1226(84)90009-2.


In a retrospective study of 28 patients whose venous leg ulcers had been treated with human amnion prior to split-skin grafting, the rate of recurrence of ulceration was 50% at 1 year. Repeated grafting of ulcers which recurred rapidly after the first skin graft was worthwhile as many then remained healed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amnion / transplantation*
  • Humans
  • Leg Ulcer / surgery*
  • Postoperative Complications
  • Recurrence
  • Skin Transplantation
  • Wound Healing