Degree of addiction and effectiveness of nicotine gum therapy for smoking

Am J Psychiatry. 1984 Jun;141(6):790-1. doi: 10.1176/ajp.141.6.790.


In a double-blind trial, 48 smokers completed a nicotine tolerance questionnaire and then received nicotine gum or placebo during smoking cessation. Subjects given active gum were more likely to remain abstinent if their questionnaire responses indicated high nicotine dependence.

Publication types

  • Clinical Trial
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chewing Gum*
  • Clinical Trials as Topic
  • Double-Blind Method
  • Humans
  • Nicotine / administration & dosage
  • Nicotine / therapeutic use*
  • Placebos
  • Smoking Prevention*
  • Substance-Related Disorders / diagnosis*
  • Substance-Related Disorders / psychology
  • Surveys and Questionnaires
  • Tobacco Use Disorder / psychology
  • Tobacco Use Disorder / rehabilitation


  • Chewing Gum
  • Placebos
  • Nicotine